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1-Oleoyl Lysophosphatidic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1-Oleoyl Lysophosphatidic Acid图片
CAS NO:65528-98-5
包装与价格:
包装价格(元)
5mg (22.91 mM * 500 μL in Ethanol)电议
10mg (22.91 mM * 1 mL in Ethanol)电议

产品名称
1-Oleoyl-sn-glycero-3-phosphate
1-Oleoyl-LPA
产品介绍
1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) 是一种丰富的溶血磷脂酸种类,由于其对 LPA 受体 (LPA receptors) 的强亲和力,具有很高的生物活性。1-Oleoyl lysophosphatidic acid 在大多数实验室中常用作 LPA 受体激活的试剂。1-Oleoyl lysophosphatidic acid 可增加 SRE 驱动的 β-galactosidase 的活性。
生物活性

1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) is an abundant lysophosphatidic acid (LPA) species with high biological activity due to its strong affinity for theLPA receptors. 1-Oleoyl lysophosphatidic acid is commonly used in most laboratories as a reagent for LPA receptor activation[1]. 1-Oleoyl lysophosphatidic acid increases SRE-driven β-galactosidase activity[2].

体内研究
(In Vivo)

1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) (0.4-2 μg; i.c.v.; 9-week-old male Wistar rats) induces anxiety-like responses in the elevated plus maze (EPM) under novelty conditions[1].

Animal Model:9-week-old male Wistar rats[1]
Dosage:0.4-2 μg
Administration:I.c.v.
Result:Reduced open arm exploration under novelty conditions and had no effect under habituated conditions in the EPM.
分子量

436.52

性状

Liquid

Formula

C21H41O7P

CAS 号

65528-98-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Solution, -20°C, 2 years