3-Propylxanthine 作为一种选择性和竞争性 A2B 受体拮抗剂，Ki 为 7 μM。
| Cas No. | 41078-02-8 |
| 别名 | 恩丙茶碱；恩普菲林 |
| Canonical SMILES | O=C(C(N=CN1)=C1N2CCC)NC2=O |
| 分子式 | C8H10N4O2 |
| 分子量 | 194.2 |
| 溶解度 | DMF: 20 mg/mL,DMSO: 30 mg/mL,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/mL,Ethanol: 0.5 mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 µM for A1, A2A, and A2B, respectively) and cAMP phosphodiesterase (Ki = 42 µM). Through these actions, 3-propylxanthine induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness. |
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