CAS NO: | 192322-50-2 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | CGP71683 hydrochloride is a competitiveneuropeptide Y5 receptorantagonist with aKiof 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes. | ||||||||||||||||
IC50& Target | Ki: 1.3 nM (Y5 receptor), 200 nM (Y2 receptor), >4000 nM (Y1 receptor)[1] | ||||||||||||||||
体外研究 (In Vitro) | CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Kiof 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes[1]. | ||||||||||||||||
体内研究 (In Vivo) | CGP71683 (15 nmol/rat, icv, twice daily) shows anorexigenic effect, reducing food intake and bady weight of fed rats. CGP71683 causes 3-times higher serum total T4 and 37% increase in free T4 in the fasted rats than in the fasted controls rats[2]. | ||||||||||||||||
分子量 | 512.07 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C26H30ClN5O2S | ||||||||||||||||
CAS 号 | 192322-50-2 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 160 mg/mL(312.46 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
|