CAS NO: | 58822-25-6 |
包装 | 价格(元) |
10 mM * 1 mL in Water | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | [Leu5]-Enkephalin is a pentapeptide with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist atopioid receptors. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Enkephalins (met- , leu-enkephalin, and enkephalin 8) and dynorphins are two classes of opioid peptides found in the spinal dorsal horn. Mu, delta, and kappa are three major subtypes of opioid receptors. Enkephalins are putative endogenous ligands for delta opioid receptors, and dynorphins are endogenous ligands for the kappa opioid receptors. Three receptor types resembling the vertebrate δ- and κ-type opioid receptors have been characterized pharmacologically in nervous tissues (e.g. Ki=18.9 nM for Leu-enkephalin) and localized by autoradiography at CHH terminals in the SG ofC. maenas[1].Leucine-enkephalin is a pentapeptides with morphine like properties, naturally present in mammalian brain[2]. | ||||||||||||||||
分子量 | 555.62 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C28H37N5O7 | ||||||||||||||||
CAS 号 | 58822-25-6 | ||||||||||||||||
Sequence | Tyr-Gly-Gly-Phe-Leu | ||||||||||||||||
Sequence Shortening | YGGFL | ||||||||||||||||
中文名称 | [Leu5]-脑啡肽 | ||||||||||||||||
结构分类 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : ≥ 150 mg/mL(269.97 mM) H2O : 100 mg/mL(179.98 mM;Need ultrasonic) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
*以上所有助溶剂都可在本网站选购。 |