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14,15-EE-5(Z)-E
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
14,15-EE-5(Z)-E图片
CAS NO:519038-92-7
包装与价格：
包装价格(元)
25μg电议
50μg电议
100μg电议
500μg电议

产品介绍
Cas No.519038-92-7
Canonical SMILESCCCCC[C@H]1O[C@H]1CCCCCCC/C=C\CCCC(=O)O
分子式C20H36O3
分子量324.5
溶解度DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 0.5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-5(Z)-E is a structural analog of 14,15-epoxyeicosatrienoic acids (14,15-EET) that antagonizes EET-induced relaxation of vascular smooth muscle. Relaxation of U46619-constricted bovine arteries by 14,15-EET could be inhibited approximately 80% by 14,15-EE-5(Z)-E at a concentration of 10 µM. 14,15-EE-5(Z)-E does not appear to antagonize nitric oxide- or iloprost-mediated vascular relaxation.