Modipafant (UK-80067), the (+)-enantiomer of UK-74505, is a potent, orally active, and selective platelet-activating factor(PAF)antagonist. Modipafant exhibits approximately double the intrinsic potency of UK-74505^[1][2].

when preincubated with rabbit platelets, the potency of antagonizing PAF induced aggregation increased markedly when preincubation time with Modipafant was increased from 2 min (IC₅₀=5.6 nM) to 60 min (IC₅₀=0.34 nM)^[2].

605.09

C₃₄H₂₉ClN₆O₃

122957-06-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.