CAS NO: | 883050-24-6 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | CCG-50014 is the most potent againstthe regulator of G-protein signaling protein type 4 (RGS4)(IC50=30 nM) and is >20-fold selective forRGS4over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site[1]. CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test[2]. | ||||||||||||||||
IC50& Target |
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体内研究 (In Vivo) | CCG50014 (10, 30, or 100 nM) attenuates the nociceptive responses during the late phase in a dose-dependent manner[2]. | ||||||||||||||||
分子量 | 316.35 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C16H13FN2O2S | ||||||||||||||||
CAS 号 | 883050-24-6 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 62.5 mg/mL(197.57 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |