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3,4'-Dihydroxyflavone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3,4'-Dihydroxyflavone图片
CAS NO:14919-49-4
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议

产品介绍
3,4'-Dihydroxyflavone(3,4'-DHF)是一种具有口服活性的黄酮类化合物，具有抗病毒活性，如，甲型流感病毒(InfluenzaAvirus)。
Cas No.14919-49-4
别名3,4'-二羟基黄酮,3,4'-DHF
Canonical SMILESO=C1C(O)=C(C2=CC=C(O)C=C2)OC3=C1C=CC=C3
分子式C15H10O4
分子量254.24
溶解度DMSO : ≥ 155 mg/mL (609.66 mM);Water :< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1].

3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1]. Animal Model: 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1].

[1]. Hossain MK, et al. Antiviral activity of 3,4'-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6.