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(+)-(3R,8S)-Falcarindiol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(+)-(3R,8S)-Falcarindiol图片
CAS NO:225110-25-8
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
(+)-(3R,8S)-Falcarindiol是从胡萝卜中得到的聚乙炔，具有抗分歧杆菌(antimycobacterial)作用，对MycobacteriumtuberculosisH37Ra的最低抑制浓度MIC和IC50值分别为24μM和6μM。具有抗肿瘤和抗炎作用。
Cas No.225110-25-8
别名镰叶芹二醇,(3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol
Canonical SMILESC=C[C@@H](O)C#CC#C[C@@H](O)/C=C\CCCCCCC
分子式C17H24O2
分子量260.37
溶解度Chloroform: soluble,DMSO: soluble,Ethanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(+)-(3R,8S)-Falcarindiol is a polyacetylene found in carrots, has antimycobacterial activity, with an IC50 of 6 μM and MIC of 24 μM against Mycobacterium tuberculosis H37Ra[1][2]. Antineoplastic and anti-inflammatory activity[2]. IC50: 6 μM (Mycobacterium tuberculosis H37Ra)[1]

[1]. O'Neill T, et al. The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins. J Ethnopharmacol. 2013 May 2;147(1):232-7. [2]. Kobaek-Larsen M, et al. Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer. BMC Res Notes. 2018 Jun 27;11(1):411.