SSTR5antagonist 2 hydrochloride is a highly potent, oral active andselective somatostatin (receptor) subtype 5 (SSTR5)antagonist and has potential for the research of type 2 diabetes mellitus (T2DM)^[1].

SSTR5 antagonist 2 (compound 10) (10 mg/kg, orally) hydrochloride increases both total and active circulating incretin hormone GLP1 levels in mice at a dose of 10 mg/kg^[1].
SSTR5 antagonist 2 hydrochloride increases pancreatic insulin secretion as well as total and active GLP1 release, and demonstrates synergistic effects in combination with DPP4 inhibitors^[1].

583.09

Solid

C₃₂H₃₆ClFN₂O₅

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

DMSO : 33.33 mg/mL(57.16 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。