CAS NO: | 1884420-36-3 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selectivevasopressin V1 receptoragonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research[1][2][3][4][5]. | ||||||||||||||||
IC50& Target | Vasopressin V1 receptor[1] | ||||||||||||||||
体外研究 (In Vitro) | Terlipressin (25 nM; 24-72 hours; IEC-6 cells) treatment significantly improves cell viability, proliferation and apoptosis in IEC-6 cells[1]. Cell Proliferation Assay[1]
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体内研究 (In Vivo) | Using a mouse nonlethal hepatic ischemia-reperfusion (IR) model, Terlipressin administration significantly ameliorates IR-induced liver apoptosis, necrosis and inflammation[3]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 1347.48 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C56H82N16O19S2 | ||||||||||||||||
CAS 号 | 1884420-36-3 | ||||||||||||||||
Sequence | Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys4-Cys9) | ||||||||||||||||
Sequence Shortening | GGGCYFQNCPKG-NH2 (Disulfide bridge: Cys4-Cys9) | ||||||||||||||||
中文名称 | 醋酸特利加压素 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Stored under nitrogen, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 100 mg/mL(74.21 mM;Need ultrasonic) DMSO : 50 mg/mL(37.11 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
*以上所有助溶剂都可在本网站选购。 |