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Fosravuconazole(BMS-379224)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fosravuconazole(BMS-379224)图片
CAS NO:351227-64-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Fosravuconazole (BMS-379224) (BMS-379224) 是 Ravuconazole 的前药,是一种具有口服活性的广谱抗真菌剂。
Cas No.351227-64-0
别名BMS-379224; E-1224
Canonical SMILESN#CC1=CC=C(C2=CSC([C@H](C)[C@@](OCOP(O)(O)=O)(C3=CC=C(F)C=C3F)CN4N=CN=C4)=N2)C=C1
分子式C23H20F2N5O5PS
分子量547.47
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fosravuconazole is a prodrug of ravuconazole, with antifungal activity.

Fosravuconazole (BMS-379224) is a prodrug of ravuconazole, with antifungal activity[1].

Fosravuconazole (BMS-379224) is rapidly conversed to ravuconazole upon iv administration to rats. Fosravuconazole shows comparable efficacy at inhibiting C. albicans infection model in mice as orally administered ravuconazole[1].

[1]. Ueda Y, et al. Phosphonooxymethyl prodrugs of the broad spectrum antifungal azole, ravuconazole: synthesis and biological properties. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3669-72.