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2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl)sulfide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl)sulfide图片
CAS NO:137089-36-2
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
2-(E-2-decenoylamino)ethyl2-(cyclohexylethyl)sulfide是一种由压力诱发的溃疡和低毒性抑制剂，可以在压力引起的溃疡大鼠中，维持磷脂酶A2(phospholipaseA2)和前列腺素E2(prostaglandinE2)的含量水平。
Cas No.137089-36-2
Canonical SMILESCCCCCCC/C=C/C(NCCSCCC1CCCCC1)=O
分子式C20H37NOS
分子量339.58
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.

2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (compd.III-1α, 100 mg/kg, p.o.) maintains the relative content of Fr.I hexose, lipid peroxide and phospholipase A2 (PLA2) in normal level in ulcerated rats induced by water immersed restrained stress via dosing twice a day for 3 day (b.i.d. for 3 d). 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (100 mg/kg, p.o.) reduces the hexosamine content equally with the control group 4 h after the stress loading, and then markedly increases 7 h after stress loading. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) blocks the reduction of prostaglandin E2 (PGE2) and PGI2 in early phase and accelerates the increase of PGE2 and PGI2 in the late phase of the stress. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) also significantly accelerates the cell proliferation in fundic glands in gastric mucosa of mice[1].

[1]. Kohda I, et al. Further studies on the anti-ulcerogenic effects of compound, 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide. Chem Pharm Bull (Tokyo). 1991 Jul;39(7):1832-6.