| Cas No. | 1047670-51-8 |
| Canonical SMILES | O=C(C1=NN(C2=C(Cl)C=C(Cl)C=C2)C(C3=CC=C(Br)C=C3)=C1C)C4=CC=C(OC)C=C4 |
| 分子式 | C24H17BrCl2N2O2 |
| 分子量 | 516.2 |
| 溶解度 | DMF: 3 mg/ml,DMF:PBS(pH7.2) (1:2): 0.33 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). It inhibits food consumption in nonfasted mice without affecting motor activity. ABD459 reduces active food seeking for 5-6 hours after treatment, with no rebound after washout. ABD459 also diminishes rapid eye movement (REM) sleep, with no alterations of wakefulness or non-REM sleep. |
m.cnreagent.com