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α-Spinasterol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
α-Spinasterol图片
CAS NO:481-18-5
包装:1mg
市场价:903元

产品介绍
α-菠菜甾醇，从菠菜中分离出来，具有抗菌活性。
Cas No.481-18-5
别名菠甾醇
化学名(3S,5S,9R,10S,13R,14R,17R)-17-((2R,5S,E)-5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
Canonical SMILESO[C@@H]1C[C@H]2[C@@](CC1)(C)[C@@H]3C([C@H]4[C@@](CC3)(C)[C@@H]([C@@H](/C=C/[C@@H](CC)C(C)C)C)CC4)=CC2
分子式C29H48O
分子量412.69
溶解度DMF: 1 mg/ml,Ethanol: 0.25 mg/mL
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

α-Spinasterol, isolated from Spinacia oleracea, has antibacterial activity[1]. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively[2].

References:
[1]. Brusco I, et al. α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice. Br J Pharmacol. 2017 Dec;174(23):4247-4262.
[2]. Yang X, et al. A novel method for synthesis of α-spinasterol and its antibacterial activities in combination with ceftiofur. Fitoterapia. 2017 Jun;119:12-19.