CAS NO: | 162641-16-9 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | HQL-79, a potent, selective and orally active humanhematopoietic prostaglandin D synthase (H-PGDS)inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with aKdof 0.8 μM and anIC50of 6 μM. Shows no obvious effect onCOX-1,COX-2, m-PGES, or L-PGDS[1]. | ||||||||||||
IC50& Target | IC50: 6 μM (H-PGDS)[1] | ||||||||||||
体外研究 (In Vitro) | HQL-79 is a competitive inhibitor against substrate PGH2 and a non-competitive one against GSH[1]. | ||||||||||||
分子量 | 377.48 | ||||||||||||
性状 | Solid | ||||||||||||
Formula | C22H27N5O | ||||||||||||
CAS 号 | 162641-16-9 | ||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
储存方式 |
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