CAS NO: | 20231-01-0 |
包装 | 价格(元) |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | EWP 815 is a disulfiram analogue, is a potent inhibitor ofIns(1,4)P2phosphataseandIns(1,4,5)P35-phosphatase. EWP 815 also inhibits enzymedopamine β-hydroxylaseactivity[1][2]. | ||||||||
IC50& Target | Ins(1,4)P2 phosphatase; Ins(1,4,5)P3 5-phosphatase[1]; dopamine β-hydroxylase[2] | ||||||||
体外研究 (In Vitro) | EWP 815 inhibits thyrotropin-releasing hormone (TRH; 0.03 mM)-stimulated inositol phospholipid breakdown without affecting basal breakdown rates in prelabelled GH3cells with IC50s of 83 mM (soluble enzymes) and 71 mM (particulate enzymes), respectively[1]. | ||||||||
体内研究 (In Vivo) | EWP 815 (50 mg/kg; i.p.; 30 min before killed) inhibits the enzyme dopamine β-hydroxylase activity in mice[2].
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分子量 | 350.59 | ||||||||
Formula | C12H22N4S4 | ||||||||
CAS 号 | 20231-01-0 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |