CAS NO: | 760173-05-5 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Etamicastat (BIA 5-453) is a potent and reversibledopamine-β-hydroxylase(DBH) inhibitor with anIC50value of 107 nM[1]. Etamicastat can be used in the research of cardiovascular diseases[2]. | ||||||||||||||||
IC50& Target | IC50: 107 nM (DBH)[1] | ||||||||||||||||
体外研究 (In Vitro) | Etamicastat blocks the hERG current amplitude with an IC50value of 44 μg/mL (141 μM)[2]. | ||||||||||||||||
体内研究 (In Vivo) | Etamicastat (100 mg/kg; administered intraperitoneally) leads to a significant reduction of noradrenaline levels in heart with concomitant increasing in dopamine levels[1].
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Clinical Trial | |||||||||||||||||
分子量 | 311.35 | ||||||||||||||||
Formula | C14H15F2N3OS | ||||||||||||||||
CAS 号 | 760173-05-5 | ||||||||||||||||
中文名称 | 依他米司特 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |