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IDO-IN-6(NLG-1486)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IDO-IN-6(NLG-1486)图片
CAS NO:1402837-76-6
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议

产品介绍
IDO-IN-6 (NLG-1486) (NLG-1486) 是一种吲哚胺 2,3-双加氧酶 (IDO) 抑制剂,提取自专利 WO WO2012142237A1,化合物 1486,IC50<1 μM.
Cas No.1402837-76-6
别名NLG-1486
Canonical SMILESO[C@H](CC1)CC[C@]1([H])[C@@H](O)C[C@@H]2N3C(C4=C2C(F)=CC=C4)=CN=C3
分子式C18H21FN2O2
分子量316.37
溶解度DMSO : 50 mg/mL (158.04 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of<1 μM.

IDO-IN-6 (Compound 1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of<1 μM (this is the concentration of IDO-IN-6 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].

[1]. Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.