CAS NO: | 23828-92-4 |
包装 | 价格(元) |
10 mM * 1 mL in Water | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the prodrug Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is aglucocerebrosidase (GCase)chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lungautophagyand has the potential for Parkinson disease and neuronopathic Gaucher disease research[1][2]. | ||||||||||||||||
体内研究 (In Vivo) | Ambroxol hydrochloride (NA-872 hydrochloride; 1, 3, 4, 5 mM for 12 consecutive days in drinking water) results in increased brain glucocerebrosidase activity in wild-type mice, transgenic mice expressing the heterozygous L444P mutation in the murine glucocerebrosidase 1 gene, and transgenic mice overexpressing human α-synuclein[2]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 414.56 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C13H19Br2ClN2O | ||||||||||||||||
CAS 号 | 23828-92-4 | ||||||||||||||||
中文名称 | 盐酸氨溴索 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 8.33 mg/mL(20.09 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |