CAS NO: | 864084-88-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Opiorphin, an opioid peptide, is a potentenkephalin-inactivating zinc ectopeptidases in humaninhibitor. Opiorphin inhibits two enkephalin-catabolizing ectoenzymes, human neutral ecto-endopeptidase,hNEP(EC 3.4.24.11) with anIC50value of 11 μM, and human ecto-aminopeptidase,hAP-N(EC 3.4.11.2). Opiorphin displays potent analgesic activity by activating endogenous opioid-dependent transmission[1][2]. | ||||||||
体外研究 (In Vitro) | Opiorphin (1-100 μM; the mouse isolated colon) causes contractile effects in mouse distal colon in a concentration-dependent manner and enhances the contractile response induced by Met-enkephalin[1]. | ||||||||
体内研究 (In Vivo) | Opiorphin (1.25-10 μg/kg; ICV; 0-60 min; male Kunming mice) induces potent analgesic effect in a dose- and time-dependent manner (ED50=3.22 μg/kg)[1].
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分子量 | 692.77 | ||||||||
Formula | C29H48N12O8 | ||||||||
CAS 号 | 864084-88-8 | ||||||||
Sequence Shortening | QRFSR | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |