TrxR-IN-4 (Compound 1b) 是一种有效的TrxR抑制剂。TrxR-IN-4 通过激活内质网应激 (ERS) 诱导 HepG2 细胞凋亡。TrxR-IN-4 通过下调 TrxR 表达和炎症水平改善体内 CCl4 诱导的肝损伤。
生物活性 | TrxR-IN-4 (Compound 1b) is a potent inhibitor ofTrxR. TrxR-IN-4 induces HepG2 cellsapoptosisby activating the endoplasmic reticulum stress (ERS). TrxR-IN-4 improves the CCl4-induced liver damage in vivo by down-regulation ofTrxRexpression and inflammation level[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |