包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
生物活性 | Harmane-d1 is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity forI1-Imidazoline receptor(IC50=30 nM) overα2-adrenoceptor(IC50=18 μM). Harmane is also a potent and selective inhibitor ofmonoamine oxidase(MAO)(IC50s=0.5 and 5 μM forhuman MAO A/B, respectively)[1][2][3][4]. | ||||||||||||||||
体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. | ||||||||||||||||
分子量 | 183.23 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C12H9DN2 | ||||||||||||||||
中文名称 | 哈尔满碱 d1 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | -20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 50 mg/mL(272.88 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |