他唑巴坦 (CL-298741) (CL-298741) 是一种有效的 β-内酰胺酶抑制剂和青霉素抗生素。
Cas No. | 89786-04-9 |
别名 | 他唑巴坦; 三唑巴坦; 他唑巴坦酸; CL-298741; YTR-830H |
Canonical SMILES | O=C([C@@H]([C@@](CN1N=NC=C1)(C)S([C@]2([H])C3)(=O)=O)N2C3=O)O |
分子式 | C10H12N4O5S |
分子量 | 300.29 |
溶解度 | DMSO : ≥ 35 mg/mL (116.55 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Tazobactam is a beta Lactamase Inhibitor with antibacterial activityTarget: AntibacterialTazobactam is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as its sodium salt, Tazobactam sodium.Tazobactam is combined with the extended spectrum β-lactam antibiotic piperacillin in the drug piperacillin/Tazobactam, one of the preferred antibiotic treatments for nosocomial pneumonia caused by Pseudomonas aeruginosa. Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express β-lactamase and would normally degrade piperacillin. Tazobactam is derived from the penicillin nucleus and is a penicillinic acid sulfone. |