CAS NO: | 2159141-27-0 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
生物活性 | Semorinemab (RG 6100) is an anti-TauhumanizedIgG4monoclonal antibody, targets the N-terminal portion of theTau protein. Semorinemab binds with human Tau with aKdvalue of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease[1]. | ||||||||
体外研究 (In Vitro) | Semorinemab 与人 Tau 蛋白和重组食蟹猴 Tau 蛋白结合的 Kd值分别为 3.8 和 11.2 nM[1]。Semorinemab 阻止神经元摄取低聚 Tau[1]。 | ||||||||
体内研究 (In Vivo) | Semorinemab (3,10 和 30 mg/kg;腹腔注射,每周一次,持续 13 周) 减少 Tau 病状的转基因 (Tg) 小鼠模型中 Tau 的积累[1]。
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CAS 号 | 2159141-27-0 | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |