CAS NO: | 201529-58-0 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | (-)Clausenamide is an active alkaloid isolated from the leaves of Clausena lansium (Lour.) Skeels, and improves cognitive function in both normal physiological and pathological conditions. (-)Clausenamide inhibitsβ-amyloid(Aβ) toxicity, blocking neurofibrillary tangle formation by inhibiting the phosphorylation oftauprotein. (-)Clausenamide exerts a significant neuroprotective activity against Aβ25-35. (-)Clausenamide can be used for researching Alzheimer's disease (AD)[1][2][3]. |
体外研究 (In Vitro) | (-)Clausenamide (10 and 100 μM) reverses the overload in [Ca2+]ilevel stimulated by Aβ25-35, and reduces Aβ-mediated cell apoptosis in PC12 cells[3]. |
分子量 | 297.35 |
Formula | C18H19NO3 |
CAS 号 | 201529-58-0 |
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |