CAS NO: | 1079274-94-4 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Utatrectinib (AZD-7451) is a potent, selective and orally activeTrkinhibitor. Utatrectinib blocksTrkCactivation and associated tumorigenic behaviors[1]. | ||||||||||||||||
体外研究 (In Vitro) | Utatrectinib (100 nM, 22 h) inhibits the migration of TrkC-expressing U2SO cells[2]. Cell Migration Assay[2]
Western Blot Analysis[3]
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体内研究 (In Vivo) | Utatrectinib (50 mg/kg, p.o., daily) suppresses adenoid cystic carcinoma (ACC) tumor growth in ACCX6 xenograft nu/nu mice model[2].
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Clinical Trial | |||||||||||||||||
分子量 | 382.39 | ||||||||||||||||
Formula | C18H19FN8O | ||||||||||||||||
CAS 号 | 1079274-94-4 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |