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β-Anhydroicaritin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
β-Anhydroicaritin图片
CAS NO:38226-86-7
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
β-Anhydroicaritin 提取自 Boswellia carterii Birdware,具有重要的生物学和药理学作用,例如抗骨质疏松症,雌激素调节和抗肿瘤特性。β-Anhydroicaritin 改善牙周组织的降解,抑制糖尿病大鼠 TNF-α 和 MMP-3 的合成和分泌。β-Anhydroicaritin 减少腹膜炎小鼠 NO,IL-10,TNF-α,MCP-1 和 IL-6 的过量产生。β-Anhydroicaritin 抑制细胞内 Ca2+ 的升高,并显着降低 iNOS 蛋白的表达。
Cas No.38226-86-7
别名脱水淫羊藿素(淫羊藿素)
Canonical SMILESO=C1C2=C(O)C=C3C(CCC(C)(C)O3)=C2OC(C4=CC=C(OC)C=C4)=C1O
分子式C21H20O6
分子量368.38
溶解度DMSO: 8.33 mg/mL (22.61 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

β-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties[1]

[1]. Nguyen VS, et al. Synthesis of Icaritin and β-anhydroicaritin Mannich Base Derivatives and Their Cytotoxic Activities on Three Human Cancer Cell Lines. Anticancer Agents Med Chem. 2017;17(1):137-142 [2]. Wu Y, et al. Effect of β-anhydroicaritin on the expression levels of tumor necrosis factor-α and matrix metalloproteinase-3 in periodontal tissue of diabetic rats. Mol Med Rep. 2015 Aug;12(2):1829-37. [3]. Lai X, et al. Protective effect of anhydroicaritin against peritonitis in mice. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2013 Oct;29(10):1036-9.