CAS NO: | 2172617-15-9 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
Cas No. | 2172617-15-9 |
Canonical SMILES | O=C1N(C2=NC(NC3=CC=C(C=C3OC)N4CCN(CC4)C)=NC=C2CN1C5=C(C=CC=C5C)C)C6CCC6 |
分子式 | C30H37N7O2 |
分子量 | 527.66 |
溶解度 | DMSO: 62.5 mg/mL (118.45 mM); Water:< 0.1 mg/mL (insoluble) |
储存条件 | Store at -20°C, protect from light, stored under nitrogen |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1]. IC50: 6.56 nM/1.77 nM/20.5 nM (SIK1/2/3)[1]. [1]. Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184. |