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MethADP
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MethADP图片
CAS NO:3768-14-7
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
MethADP 是一个特异性的 CD73 抑制剂。
Cas No.3768-14-7
别名腺苷5'-(Α,Β-亚甲基)二磷酸,Adenosine 5'-(α,β-methylene)diphosphate
Canonical SMILESO[C@@H]([C@H]([C@H](N1C=NC2=C(N=CN=C21)N)O3)O)[C@H]3COP(O)(CP(O)(O)=O)=O
分子式C11H17N5O9P2
分子量425.23
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MethADP is a specific CD73 inhibitor. CD73[1].

MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation[1].

[1]. Mohlin C, et al. Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells. Pharmacology. 2009;84(4):196-202.