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Ursodeoxycholic acid-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ursodeoxycholic acid-d5图片
CAS NO:93701-18-9
包装与价格:
包装价格(元)
2.5mg电议
1mg电议
5mg电议
10mg电议

产品名称
Ursodiol-d5
UDCA-d5
产品介绍
Ursodeoxycholic acid-d5 (Ursodiol-d5) 是 Ursodeoxycholic acid 的氘代物。Ursodeoxycholic acid (Ursodeoxycholate) 是由肠道细菌转化 (cheno)脱氧胆酸而产生的一种次级胆汁酸,是肠道屏障完整性的关键调节因子,对脂质代谢至关重要。Ursodeoxycholic acid 作为信号分子,通过与胆汁酸激活的受体相互作用发挥作用,包括G蛋白偶联的胆汁酸受体5 (TGR5GPCR19) 和法尼酯X受体 (FXR)。Ursodeoxycholic acid 可用于多种肝脏和胃肠道疾病的研究。具有口服活性。
生物活性

Ursodeoxycholic acid-d5 (Ursodiol-d5) is the deuterium labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5,GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

397.60

Formula

C24H35D5O4

CAS 号

93701-18-9

中文名称

熊去氧胆酸 d5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.