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Azido-PEG9-acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Azido-PEG9-acid图片
CAS NO:1670249-37-2
包装与价格：
包装价格(元)
100mg电议
250mg电议

产品介绍
Azido-PEG9-acid 是一种不可降解 (non-cleavable) 的含 9 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。Azido-PEG9-acid 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。
Cas No.1670249-37-2
分子式C21H41N3O11
分子量511.56
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Azido-PEG9-acid is a non-cleavable 9 unit PEGADClinker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].