CAS NO: | 93106-59-3 |
包装 | 价格(元) |
10 mM * 1 mL in Water | 电议 |
500mg | 电议 |
5 g | 电议 |
10 g | 电议 |
50 g | 电议 |
生物活性 | Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effectiveantibioticwith an MIC90of 0.312 μg/mL forMycoplasma bovis. Enrofloxacin monohydrochloride shows inhibitory activity against vaccinia virus (VV). | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Mycoplasma bovisis a worldwide pathogen, causative agent of pneumonia, mastitis, arthritis, and a variety of other symptoms in cattle. The antibiotic susceptibility profiles of the Hungarian strains are consistent within the tested group of fluoroquinolones. Three isolates (MYC44, MYC45 and MYC46) have high MIC values (≥10 μg/mL) to Enrofloxacin, while the rest of the strains are inhibited by Enrofloxacin with MICs ≤0.312 or 0.625 μg/mL[1]. | ||||||||||||||||
体内研究 (In Vivo) | Mice (n=80) undergo transient middle cerebral artery occlusion (MCAo) with reperfusion after 60 minutes. After MCAo, animals are randomly assigned to receive either a daily preventive medication (n=26, Enrofloxacin) starting at the day of MCAo or a therapeutic medication (n=25; Enrofloxacin) after diagnosis of lung infection. Standard treatment started immediately after the appearance of clinical signs (general health score>6) usually between day 4 and 6 after stroke. Both, preventive and standard antibiotic treatment using Enrofloxacin improve survival in a similar way compared with placebo treatment[2]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 395.86 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C19H23ClFN3O3 | ||||||||||||||||
CAS 号 | 93106-59-3 | ||||||||||||||||
中文名称 | 恩诺沙星单盐酸盐;恩罗沙星盐酸盐;恩氟沙星盐酸盐;恩氟喹啉羧酸盐酸盐;恩氟奎林羧酸盐酸盐 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 7.14 mg/mL(18.04 mM;Need ultrasonic) DMSO :< 1 mg/mL (ultrasonic;warming;heat to 60℃)(insoluble or slightly soluble) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |