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Sparfloxacin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sparfloxacin图片
CAS NO:110871-86-8
包装与价格:
包装价格(元)
100mg电议
500mg电议
1 g电议
5 g电议

产品名称
司帕沙星
CI-978
AT-4140
产品介绍
Sparfloxacin (CI-978) 是氟喹诺酮类抗菌素。
生物活性

Sparfloxacin (CI-978) is a fluoroquinoloneantibiotic, shows broad and potent antibacterial activity.

IC50& Target

Quinolone

 

体外研究
(In Vitro)

Sparfloxacin (CI-978) shows broad and potent antibacterial activity. Its MICs for 90% of the strains tested are 0.1 to 0.78 μg/ml against gram-positive organisms, such as members of the genera Staphylococcus , Streptococcus and Enterococcus , and 0.0125 to 1.56 μg/ml against gram-negative organisms, such as members of the family Enterobacteriaceae and the genera Pseudomona . Its MICs are 0.025 to 0.78 μg/ml against glucose nonfermenters, 0.2 to 0.78 μg/ml against anaerobes, 0.0125 to 0.05 μg/ml against Legionella. Sparfloxacin (CI-978) showed good oral efficacy against systemic infections with Staphylococcus aureus , Streptococcus pyogenes , Streptococcus pneumoniae , Escherichia coli , and Pseudomonas aeruginosa in mice[1]. Sparfloxacin targets DNA gyrase and inhibits DNA synthesis[2].

分子量

392.40

性状

Solid

Formula

C19H22F2N4O3

CAS 号

110871-86-8

中文名称

司帕沙星

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

0.1 M NaOH : 50 mg/mL(127.42 mM;ultrasonic and adjust pH to 11 with NaOH)

DMSO : 3.33 mg/mL(8.49 mM;Need ultrasonic)

H2O : 0.67 mg/mL(1.71 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM2.5484 mL12.7421 mL25.4842 mL
5 mM0.5097 mL2.5484 mL5.0968 mL
10 mM0.2548 mL1.2742 mL2.5484 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month (protect from light)。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。