CAS NO: | 110871-86-8 |
包装 | 价格(元) |
100mg | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | Sparfloxacin (CI-978) is a fluoroquinoloneantibiotic, shows broad and potent antibacterial activity. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Sparfloxacin (CI-978) shows broad and potent antibacterial activity. Its MICs for 90% of the strains tested are 0.1 to 0.78 μg/ml against gram-positive organisms, such as members of the genera Staphylococcus , Streptococcus and Enterococcus , and 0.0125 to 1.56 μg/ml against gram-negative organisms, such as members of the family Enterobacteriaceae and the genera Pseudomona . Its MICs are 0.025 to 0.78 μg/ml against glucose nonfermenters, 0.2 to 0.78 μg/ml against anaerobes, 0.0125 to 0.05 μg/ml against Legionella. Sparfloxacin (CI-978) showed good oral efficacy against systemic infections with Staphylococcus aureus , Streptococcus pyogenes , Streptococcus pneumoniae , Escherichia coli , and Pseudomonas aeruginosa in mice[1]. Sparfloxacin targets DNA gyrase and inhibits DNA synthesis[2]. | ||||||||||||||||
分子量 | 392.40 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C19H22F2N4O3 | ||||||||||||||||
CAS 号 | 110871-86-8 | ||||||||||||||||
中文名称 | 司帕沙星 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) | ||||||||||||||||
溶解性数据 | In Vitro: 0.1 M NaOH : 50 mg/mL(127.42 mM;ultrasonic and adjust pH to 11 with NaOH) DMSO : 3.33 mg/mL(8.49 mM;Need ultrasonic) H2O : 0.67 mg/mL(1.71 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |