CAS NO: | 105114-22-5 |
包装: | 1mg |
市场价: | 3916元 |
Cas No. | 105114-22-5 |
Canonical SMILES | O=C1NCC2=C1C(C(C=CC=C3)=C3N4[C@@]5([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)=C4C6=C2C7=C(C=CC=C7)N6 |
分子式 | C26H23N3O5 |
分子量 | 457.5 |
溶解度 | DMSO: soluble,Ethanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | K252d is an indolocarbazole alkaloid found inNocardiopsis.1It is a PKC inhibitor that inhibits PKC isolated from rat brain (IC50= 350 nM). It also inhibits calcium- and calmodulin-dependent phosphodiesterase isolated from bovine heart (IC50= 46.2 µM). 1.Nakanishi, S., Matsuda, Y., Iwahashi, K., et al.K-252b, c and d, potent inhibitors of protein kinase C from microbial originJ. Antibiot. (Tokyo) 39(8)1066-1071(1986) |