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Keracyanin(chloride)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Keracyanin(chloride)图片
CAS NO:18719-76-1
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
角花青素（氯化物）（Cyanidin 3-rutinoside chloride）是一种花青素，具有抗氧化活性。
Cas No.18719-76-1
别名花青素鼠李葡糖苷,Cyanidin 3-rutinoside
化学名3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-1-benzopyrylium, monochloride
Canonical SMILESOC(C(O)=C1)=CC=C1C2=[O+]C3=CC(O)=CC(O)=C3C=C2O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)O4.[Cl-]
分子式C27H31O15•Cl
分子量631
溶解度20 mg/ml in DMF, 25 mg/ml in DMSO, 1 mg/ml in Ethanol, 2 mg/ml in PBS (pH 7.2):
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Keracyanin (chloride) is a polyphenolic anthocyanin found naturally in many plants. It has high antioxidant activity, protecting erythrocytes from apoptosis. [1] [2] However, keracyanin (chloride) impairs growth and induces apoptosis in the highly tumorigenic RE-149 DHD cell line. [3] It inhibits a range of mammalian and bacterial proteases, including neutrophil elastase, matrix metalloproteinase-1 (MMP-1), and MMP-9 at concentrations of 6.25-50 &#181g/ml. [4] When added to food, keracyanin (chloride) significantly reduces body weight gain, resistance to insulin, and lipid accumulation in mice fed a high-fat diet. [5]

Reference:
[1]. Tyl, C.E., and Bunzel, M. Antioxidant activity-guided fractionation of blue wheat (UC66049 Triticum aestivum L.). Journal of Agricultural and Food Chemistry 60(3), 731-739 (2012).
[2]. Zhang, J., Hou, X., Ahmad, H., et al. Assessment of free radicals scavenging activity of seven natural pigments and protective effects in AAPH-challenged chicken erythrocytes. Food Chemistry 145, 57-65 (2014).
[3]. Zikri, N.N., Riedl, K.M., Wang, L.S., et al. Black raspberry components inhibit proliferation, induce apoptosis, and modulate gene expression in rat esophageal epithelial cells. Nutrition and Cancer 61(6), 816-826 (2009).
[4]. Santos, J., La, V.D., Bergeron, C., et al. Inhibition of host- and bacteria-derived proteinases by natural anthocyanins. J.Periodontal.Res. 46(5), 550-557 (2011).
[5]. Wu, T., Qi, X., Liu, Y., et al. Dietary supplementation with purified mulberry (Morus australis Poir) anthocyanins suppresses body weight gain in high-fat diet fed C57BL/6 mice. Food Chemistry 141(1), 482-487 (2013).