CM037 是 ALDH1A1（醛脱氢酶 1A1）的选择性抑制剂，IC50 为 4.6 μM。
| Cas No. | 896795-60-1 |
| 别名 | A37 |
| Canonical SMILES | O=C1N(CCCN2CCCC2)C(SCC(OCC)=O)=NC3=C1SC4=C3C=CC=C4 |
| 分子式 | C21H25N3O3S2 |
| 分子量 | 431.6 |
| 溶解度 | DMF: 10 mg/ml,DMF:PBS (pH 7.2); (1:7): 0.125 mg/ml,DMSO: 2.5 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CM037 is a selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1; IC50 = 4.6 µM). It is selective for ALDH1A1 over eight other ALDH isoenzymes at a concentration of 20 µM. CM037 is a competitive inhibitor against acetaldehyde with a Ki value of 0.23 µM. |
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