CAS NO: | 5966-29-0 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
A bioactive sphingolipid
Cas No. | 5966-29-0 |
别名 | Cer(d18:0/16:0) ; Ceramide (d18:0/16:0); N-hexadecanoyl-D-erythro-Dihydrosphingosine; N-Palmitoyl Sphinganine |
化学名 | N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-hexadecanamide |
Canonical SMILES | O=C(CCCCCCCCCCCCCCC)N[C@@H](CO)[C@H](O)CCCCCCCCCCCCCCC |
分子式 | C34H69NO3 |
分子量 | 539.9 |
溶解度 | Chloroform:Methanol (5:1): Soluble,DMSO: Soluble,Ethanol: Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
文献引用 | |
产品描述 | C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome C oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability to induce apoptosis, cytochrome C release, or channel formation in phospholipid membranes in the absence of C16 ceramide. Reference: |