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Ampicillin trihydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ampicillin trihydrate图片
CAS NO:7177-48-2
包装与价格:
包装价格(元)
500mg电议
1 g电议
5 g电议

产品名称
D-(-)-α-Aminobenzylpenicillin trihydrate
产品介绍
Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) 是一种广谱 β-内酰胺类抗生素,可对抗多种革兰氏阳性和革兰氏阴性细菌。
生物活性

Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactamantibioticagainst a variety of gram-positive and gram-negativebacteria.

IC50& Target

β-lactam

 

体外研究
(In Vitro)

Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) inhibits the growth ofE. coliof swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin trihydrate is 2.5 uG/mL[1].

体内研究
(In Vivo)

Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1].
Ampicillin trihydrate produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2].
Ampicillin trihydrate provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin trihydrate reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with Ampicillin trihydrate significantly reduces medial hippocampal cell death following global forebrain ischemia[3].

Clinical Trial
分子量

403.45

性状

Solid

Formula

C16H25N3O7S

CAS 号

7177-48-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro: 

H2O : 4.55 mg/mL(11.28 mM;ultrasonic and warming and heat to 60℃)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM2.4786 mL12.3931 mL24.7862 mL
5 mM0.4957 mL2.4786 mL4.9572 mL
10 mM0.2479 mL1.2393 mL2.4786 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture and light)。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。