| CAS NO: | 579-56-6 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 200mg | 电议 |
| Cas No. | 579-56-6 |
| 别名 | 异舒普林盐酸盐；盐酸异克舒令 |
| 化学名 | 4-hydroxy-α-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-benzenemethanol, monohydrochloride |
| Canonical SMILES | OC1=CC=C(C(O)C(C)NC(C)COC2=CC=CC=C2)C=C1.Cl |
| 分子式 | C18H23NO3o HCl |
| 分子量 | 337.8 |
| 溶解度 | ≥ 16.3mg/mL in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Isoxsuprine is a modulator of β2 adrenoreceptor and has agonist or antagonist effects. The β2 adrenoceptors are a class of G protein-coupled receptors that are targets for epinephrine. Many cells possess these receptors, the binding of epinephrine to the receptor will generally stimulates the sympathetic nervous system, resulting in muscle relaxation, vasodilation, diverting blood flow from non-essential organs to skeletal muscle and mobilizing energy [1]. As a modulator of β2 adrenoreceptor, Isoxsuprine is used as a vasodilator as well as smooth muscle modifier in humans. In vitro neuroprotection experiment, when administered up to an hour after reoxygenation, Isoxsuprine demonstrated no loss of neuron efficacy [2].. In vivo animal stroke model, 1 mg/kg isoxsuprine was administered after a 90-minute occlusion of the right middle cerebral artery by IV injection at reperfusion. Total infarct volume in isoxsuprine-treated group was 137±18 mm3 compared to 279±25 mm3 in control group [2]. References: |
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