Obtusifoliol

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Obtusifoliol

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

16910-32-0

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Obtusifoliol 是一种特异的CYP51抑制剂，Obtusifoliol 对布鲁氏锥虫 (TB) 和人 CYP51 的亲和力的K_d值分别为 1.2 μM 和 1.4 μM。

生物活性

Obtusifoliol is a specificCYP51inhibitor, Obtusifoliol shows the affinity withK_dvalues of 1.2 μM and 1.4 μM forTrypanosomabrucei(TB) and humanCYP51, respectively^[1].

IC₅₀& Target

CYP51

Trypanosoma

体外研究
(In Vitro)

Obtusifoliol (0.1-100 μM; 48 hours) inhibit MCF-7 and MDA-MB231 breast cancer cells proliferation via arresting cell cycle progression and induction of apoptosis^[1].

Cell Viability Assay^[2]

Cell Line:	MCF-7; MDA-MB231 breast cancer cells
Concentration:	0.1, 1, 10, 40, 80, and 100 μM
Incubation Time:	48 hours
Result:	Inhibited MCF-7 and MDA-MB231 breast cancer cells proliferation.

分子量

426.72

Formula

C₃₀H₅₀O

CAS 号

16910-32-0

结构分类

Others

来源

Plants
Gramineae
Sorghum bicolor(Linn.) Moench

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.