J 113863 是一种有效的选择性 CCR1 (CD18) 拮抗剂，对人和小鼠 CCR1 受体的 IC50 值分别为 0.9 nM 和 5.8 nM。
| Cas No. | 353791-85-2 |
| 化学名 | (1r,4r)-1-((E)-cyclooct-1-en-1-ylmethyl)-4-(2,7-dichloro-9H-xanthene-9-carboxamido)-1-ethylpiperidin-1-ium iodide |
| Canonical SMILES | ClC1=CC=C(C(C(C2=C3)C(N[C@H]4CC[N@@+](C/C5=C/CCCCCC5)(CC)CC4)=O)=C1)OC2=CC=C3Cl.[I-] |
| 分子式 | C30H37Cl2IN2O2 |
| 分子量 | 655.44 |
| 溶解度 | <65.54mg/ml in DMSO;<32.77mg/ml in ethanol |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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