CAS NO: | 4449-55-2 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
生物活性 | Warangalone is an anti-malarial compound which can inhibit the growth of both strains ofparasite3D7(chloroquine sensitive) andK1(chloroquine resistant) withIC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibitcyclic AMP-dependent protein kinase catalytic subunit(cAK) with anIC50of 3.5 μM. | ||||||||||||
IC50& Target |
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体外研究 (In Vitro) | Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively[1]. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit (cAK) with an IC50of 3.5 μM[2]. When HL-60 cells are exposed to Warangalone (30 μM) for 24 h, Warangalone induces a significant decrease (8%) in cell viability compare to controls. Warangalone also inhibits HL-60 cell growth within 24 h in a time-dependent fashion. A time-dependent increase in caspase-9 activity is observed in Warangalone-treated cells[3]. | ||||||||||||
分子量 | 404.46 | ||||||||||||
性状 | Solid | ||||||||||||
Formula | C25H24O5 | ||||||||||||
CAS 号 | 4449-55-2 | ||||||||||||
中文名称 | 攀登鱼藤异黄酮 | ||||||||||||
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
储存方式 |
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