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(Rac)-Efavirenz-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(Rac)-Efavirenz-d4图片
CAS NO:1246812-58-7
包装与价格:
包装价格(元)
1mg电议
10mg电议

产品介绍
(Rac)-Efavirenz-d4 ((Rac)-DMP 266-d4) 是 Efavirenz 氘代消旋体。Efavirenz (DMP 266) 是一种有效的野生型HIV-1 RT抑制剂,Ki为 2.93 nM,抑制 HIV-1 复制,IC95为 1.5 nM。
生物活性

(Rac)-Efavirenz-d4 ((Rac)-DMP 266-d4) is a labelled racemic Efavirenz. Efavirenz (DMP 266) is a potent inhibitor of the wild-typeHIV-1reverse transcriptasewith aKiof 2.93 nM and exhibits anIC95of 1.5 nM for the inhibition ofHIV-1replicative spread incell culture[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

319.70

Formula

C14H5D4ClF3NO2

CAS 号

1246812-58-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.