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Sphingosine(d14:1)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Sphingosine(d14:1)图片
CAS NO:24558-60-9
包装:5mg
市场价:5368元

产品介绍
Sphingosine (d14:1) (Tetradecasphing-4-enine) 是一种鞘脂，是一种有效的蛋白激酶 C (PKC) 抑制剂。鞘氨醇 (d14:1) 可防止其与 sn-1,2-二酰基甘油 (DAG)/佛波酯相互作用。
Cas No.24558-60-9
别名(2S,3R,E)-2-氨基-4-十四碳烯-1,3-二醇,Tetradecasphing-4-enine
Canonical SMILESOC[C@H](N)[C@H](O)/C=C/CCCCCCCCC
分子式C14H29NO2
分子量243.4
溶解度Chloroform: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fungus, with an EC50 value of 10.2 nM. Sphingosine (d14:1) inhibits protein kinase C (PKC) in vitro (IC50 = 7.3 mol%) as well as superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively).