Cas No. | 223507-96-8 |
Canonical SMILES | O=C(O)C1=CC=C(CON=NOCC2=CC=C(C(O)=O)C=C2)C=C1 |
分子式 | C16H14N2O6 |
分子量 | 330.3 |
溶解度 | DMF: 2 mg/ml,DMF:PBS(pH 7.2)(1:2): 0.3 mg/ml,DMSO: 10 mg/ml |
储存条件 | Store at -20°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms. SOTS-1 is an azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate. More specifically, SOTS-1 thermally decomposes to form an intermediate that reacts with oxygen at the diffusion-controlled limit to generate superoxide radical anion. The decay of SOTS-1 into the intermediate follows first order kinetics, and exhibits a half-life of 4900 seconds at physiological pH and temperature. This allows for study of the effect of superoxide on biologically relevant systems in a controlled environment that closely mimics conditions in vivo. |