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Feprazone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Feprazone图片
CAS NO:30748-29-9
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
Feprazone (DA2370; Prenazone) 是 Phenylbutazone 的类似物,是一种具有镇痛和解热活性的非甾体抗炎药。
Cas No.30748-29-9
别名非普拉宗,DA2370; Prenazone; Zepelin
Canonical SMILESO=C1C(C/C=C(C)/C)C(N(C2=CC=CC=C2)N1C3=CC=CC=C3)=O
分子式C20H20N2O2
分子量320.4
溶解度DMF: 25 mg/mL,DMSO: 25 mg/mL,Ethanol: 50 mg/mL,PBS (pH 7.2): 0.5 mg/mL,Water: 1 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

Feprazone is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor that is 10-fold selective for COX-2 over COX-1. It reduces LPS-induced prostaglandin E2 production in bovine arterial endothelial cells (IC50 = 1 μM). Oral administration of feprazone (25-100 mg/kg) reduces vascular permeability, edema, and nociception in a rat model of adjuvant-induced arthritis.