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PLX-647
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PLX-647图片
CAS NO:873786-09-5
规格:≥98%
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍
PLX-647 (PLX647) is a novel, potent and highly specific dual FMS/KIT kinase inhibitor with anticancer activity. It inhibits FMS and KIt with IC50 of 28/16 nM respectively. PLX647 shows strong selectivity compared with other kinases. PLX647 represents a unique class of kinase inhibitors with unique dual FMS and KIT specificity.
理化性质和储存条件

Name: PLX-647
CAS#: 873786-09-5
Chemical Formula: C21H17F3N4
Exact Mass: 382.14053
Molecular Weight: 382.38
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Technical InformationSynonym: PLX-647; PLX 647; PLX647.
Chemical Name: 5-((1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-(4-(trifluoromethyl)benzyl)pyridin-2-amine
InChi Key: NODCQQSEMCESEC-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H17F3N4/c22-21(23,24)17-6-3-14(4-7-17)11-26-19-8-5-15(12-27-19)10-16-13-28-20-18(16)2-1-9-25-20/h1-9,12-13H,10-11H2,(H,25,28)(H,26,27)
SMILES Code: FC(C1=CC=C(C=C1)CNC2=NC=C(CC3=CNC4=NC=CC=C43)C=C2)(F)F