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Propafenone HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Propafenone HCl图片
CAS NO:34183-22-7
包装:100mg
市场价:254元

产品介绍
普罗帕酮(盐酸盐)(SA-79(盐酸盐))是一类抗心律失常药物,可治疗与快速心跳相关的疾病,例如心房和室性心律失常。
Cas No.34183-22-7
别名盐酸普罗帕酮; SA-79 hydrochloride
化学名1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one;hydrochloride
Canonical SMILESCCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl
分子式C21H27NO3.HCl
分子量377.9
溶解度≥ 18.6mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Propafenone (hydrochloride) (SA-79 (hydrochloride)) is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.

Propafenone (hydrochloride) (SA-79 (hydrochloride)) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. According to the Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, intranasal anti-histamines are recommended for the first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Propafenone works by slowing the influx of sodium ions into the cardiac muscle cells, causing a decrease in excitability of the cells. Propafenone is more selective for cells with a high rate, but also blocks normal cells more than class Ia or Ib. Propafenone differs from the prototypical class Ic antiarrhythmic in that it has additional activity as a beta-adrenergic blocker which can cause bradycardia and bronchospasm[1].

References:
[1]. http://en.wikipedia.org/wiki/Propafenone