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Lubiprostone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lubiprostone图片
CAS NO:136790-76-6
包装与价格:
包装价格(元)
2mg电议
5mg电议
10mg电议

产品介绍
Lubiprostone (SPI-0211;RU0211) 是一种用于治疗特发性慢性便秘的胃肠道药物。
Cas No.136790-76-6
别名鲁比前列酮; RU-0211; SPI-0211
化学名7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid
Canonical SMILESCCCCC(C1(CCC2C(O1)CC(=O)C2CCCCCCC(=O)O)O)(F)F
分子式C20H32F2O5
分子量390.46
溶解度≥ 39mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lubiprostone(SPI-0211;RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation.Target: OthersLubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM). From Wikipedia.

References:
[1]. http://en.wikipedia.org/wiki/Lubiprostone